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For ray Bella pharmacokinetics of sodium piece is? Below by guangdong rabeprazole azole sodium professionals to introduce:

1. The blood drug concentration

In healthy adult male in the case on an empty stomach or after meal oral dose of 20 mg, in all the time average drug concentration in plasma dynamic as shown. In addition, medicine and after meals on an empty stomach, the subjects of pharmacokinetic parameters of average value as shown in table. Compared with hollow when taking medicine, take medicine after dinner at the peak time (tmax) delayed 1.7 hours. At the same time, absorb the individual differences are very obvious.

In addition, the healthy adult male in fasting condition order oral 10 mg, 20 mg of pharmacokinetic parameters as shown below.

2. The urine excretion

Six healthy adult male oral medicine 20 mg, urine within 72 hours after the treatment did not check out the prototype drug, metabolites carboxylic acid body and glucuronic acid combination by urinary excretion accounted for about 30% of the dosage.

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