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Rabeprazole sodium azole pharmacological effects
source:Vitalpharms Company Ltd.    Release date:2017-12-6 11:14:18

WeiXianTi 1. The rabbit outside research shows that the ray Bella azole sodium inhibits the butyryl ring adenosine monophosphate (cAMP) caused by gastric acid secretion, dog of indwelling gastric fistula caused by histamine, pentagastrin gastric acid secretion, gastric acid secretion and the basis of histamine in rats caused by gastric acid secretion have strong inhibition; Relative to other proton pump inhibitor (such as omeprazole), rabeprazole sodium azole can faster and more thoroughly with H, K - atpase separation, which can implement the recovery of gastric acid secretion inhibition faster.

2. Antiulcer effect: for all kinds of experimental ulcer of rats and experimental gastric mucosal lesions (cold bound irritability, water bondage stress reaction, pyloric ligation, sh rimantadine and hydrochloric acid - ethanol stimulus), rabeprazole azole sodium have shown strong ulcer and improve the effect of gastric mucosa lesions.

3. The resistance of helicobacter pylori: in vitro experiments showed rabeprazole azole sodium than omeprazole and LAN sola azole have stronger resistance to helicobacter pylori activity, it can be in a few sites directly against helicobacter pylori, and noncompetitive and irreversible to inhibit urease of helicobacter pylori.

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